Endocarditis Diagnostic Criteria -- Modified Duke Criteria
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Diagnostic : 0 Major Criteria and 5 Minor Criteria. Major Diagnostic Criteria. Positive blood culture for typical infective endocarditis organisms (S. EndocarditisDiagnosticCriteria--ModifiedDukeCriteria Diagnostic: 2MajorCriteriaand0MinorCriteria Diagnostic: 1MajorCriteriaand3MinorCriteria Diagnostic: 0MajorCriteriaand5MinorCriteria MajorDiagnosticCriteria Positivebloodculturefortypicalinfectiveendocarditisorganisms(S.viridansorS.bovis,HACEKorganisms,S.aureuswithoutotherprimarysite,Enterococcus),from2separatebloodculturesor2positiveculturesfromsamplesdrawn>12hoursapart,or3oramajorityof4separateculturesofblood(firstandlastsampledrawn1hourapart) Echocardiogramwithoscillatingintracardiacmassonvalveorsupportingstructures,inthepathofregurgitantjets,oronimplantedmaterialintheabsenceofanalternativeanatomicexplanation,orabscess,ornewpartialdehiscenceofprostheticvalveornewvalvularregurgitation SinglepositivebloodcultureforCoxiellaburnetiioranti-phase1IgGantibodytiter>1:800 MinorDiagnosticCriteria Predisposingheartconditionorintravenousdruguse Temp>38degreesC(100.4degreesF) Vascularphenomena:arterialemboli,pulmonaryinfarcts,mycoticaneurysms,intracranialbleed,conjunctivalhemorrhages,Janewaylesions Immunologicphenomena:glomerulonephritis,Oslernodes,Rothspots,rheumatoidfactor Microbiologicalevidence:positivebloodculturebutdoesnotmeetamajorcriterionasnotedaboveorserologicalevidenceofactiveinfectionwithorganismconsistentwithendocarditis(excludingcoagnegstaph,andothercommoncontaminants) References DurackDT,LukesAS,BrightDK.Newcriteriafordiagnosisofinfectiveendocarditis:utilizationofspecificechocardiographicfindings.DukeEndocarditisService.AmericanJournalofMedicine.96(3):200-9,1994.PubMedID:8154507 LukesAS,BrightDK,DurackDT.Diagnosisofinfectiveendocarditis.InfectDisClinNorthAm.1993Mar;7(1):1-8.Review.PubMedID:8463647 FournierPE,CasaltaJP,HabibG,etal.ModificationofthediagnosticcriteriaproposedbytheDukeEndocarditisServicetopermitimproveddiagnosisofQfeverendocarditis.AmJMed.1996;100:629.PubMedID:8678083 LiJS,SextonDJ,MickN,etal.ProposedmodificationstotheDukecriteriaforthediagnosisofinfectiveendocarditis.ClinInfectDis.2000;30:633.PubMedID:10770721 LegalNoticesandDisclaimer AllinformationcontainedinandproducedbytheEBMcalcsystemisprovided foreducationalpurposesonly.Thisinformationshouldnotbeusedforthe diagnosisortreatmentofanyhealthproblemordisease. THISINFORMATIONISNOTINTENDEDTOREPLACECLINICALJUDGMENTOR GUIDEINDIVIDUALPATIENTCAREINANYMANNER. Clickhereforfullnoticeanddisclaimer. EBMcalcisCopyright©1998-2020FoundationInternetServices [Build261279v20.3]
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