克列諾片段- 維基百科,自由的百科全書 - Wikipedia
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克列諾片段
維基百科,自由的百科全書
Klenow片段(左)與DNA聚合酶I(右)的功能結構域(PDB)
克列諾片段(Klenowfragment)或稱克列諾酶(Klenowenzyme),是1970年用(subtilisin)處理時,得到的兩個片段中分子量較大的一個,它含有605個胺基酸殘基(324~928),並有大小兩個結構域,其中大結構域(518~928)具有5'→3'聚合酶和3'→5'外切酶活性,小結構域(324~517)則具有5'→3'活性。
exo-Klenow片段[]
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延伸文章資訊
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Klenow Fragment (3´→ 5´ exo-) is an N-terminal truncation of DNA Polymerase I which retains polym...
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