CEAP 2020: Understanding and Applying the Updated ...
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CEAP classification is a discriminative instrument. Examination of a patient with chronic venous disease has to include a detailed description for each of the ... Centers Carotid Coding Dialysis Embolization EVAR HTN LimbSalvage Neurointervention Oncology Radial Regulatory Renal SFA TEVAR Venous News CurrentIssue Archive DeviceGuide Advertising About Calendar Contact Privacy Submissions Carotid Coding Dialysis Embolization EVAR HTN LimbSalvage Neurointervention Oncology Radial Regulatory Renal SFA TEVAR Venous Advertisement Advertisement July2020 CEAP2020:UnderstandingandApplyingtheUpdatedChronicVenousDiseaseClassifications Dr.TeresaCarmaninterviewsDr.FedorLurietoexploretheprocessesbywhichthe2020CEAPclassificationrevisionswerearriveduponandgaininsightsintotheirapplication. WithTeresaCarman,MD,andFedorLurie,MD ViewPDF Reprints Group5Copy CreatedwithSketch. facebook CreatedwithSketch. LinkedIn CreatedwithSketch. email-icon CreatedwithSketch. link-icon CreatedwithSketch. TeresaCarman,MD Director,VascularMedicine UHClevelandMedicalCenter Cleveland,Ohio [email protected] Disclosures:None. FedorLurie,MD,PhD,RPVI,RVT AssociateDirector,JobstVascularInstitute Toledo,Ohio AdjunctResearchProfessor,DivisionofVascularSurgery UniversityofMichigan AnnArbor,Michigan [email protected] Disclosures:None. Dr.Carman:Congratulationsonthecompletionofaveryextensive,nearly3-yearprocessrevisingtheCEAPclassificationsystem.WithCEAPlastupdatedin2004andwellingrainedintovenousdiseasepractice,whydidtheAmericanVenousForum(AVF)feelitneededanupdateafter15years? Dr.Lurie:Thankyouforprovidingmetheopportunitytotalkabouttherevisedclassification.TheCEAPclassificationisbasedonourcurrentunderstandingofvenouspathologyandmanifestationsofthechronicvenousdisorders,whichofcoursechangesovertime.Therefore,CEAPclassificationrequiresperiodicrevisions.Thefirstrevisionsweredonein2004afterCEAPhadexistedfor7years,andittooklongerforthesecondupdate.TheAVFfeltthatitwasnecessarytoanalyzewhethertheclassificationneededrevision.TherewereanumberofsuggestionsovertimethatpointedtodeficienciesandshortcomingsoftheexistingCEAPclassification.Ataskforcefirsthadtoexaminewhetherthoserevisionswereneeded,andifso,suggestwhichoneswerereasonableforupdating. Dr.Carman:Canyoubrieflyexplainhowtherevisionprocessbeganandthefourkeyconsiderationsusedfortherevision? Dr.Lurie:That’saveryimportantquestion.Everytimeyoureviseaclassification,althoughnecessary,newissuesarecreated.Withthisinmind,wedecidedthatthisrevisionshouldbedoneverycarefullytonotimpacttheprevioususesofCEAPclassification.Onemajorconsiderationwasthatarevisedorupdatedclassificationwouldbebackwardcompatible.AnypublicationsorreportsthatwereusingCEAPbeforecancontinuetobeanalyzedwithoutinterruption;whetherwehaveachievedthisisyettobeseen.Wealsodecidedthatthosechangesshouldbeevidence-based.Ifarevisionseemstobereasonablebutdoesnothavedatatosupportit,thoserevisionswouldprobablybenotaccepted.TheotherimportantpartwasthattherearepractitionerswhofeeltheCEAPclassificationisnotverypractical.Whatweconsideredveryseriouslyforeachsuggestedchangewashowpracticalthechangewas,whetheritwouldincreasetheuseofCEAPclassification,ormakeitmoredifficulttoimplement. Weunderstandthataclassificationsystemisbasicallyaconsensusdocument.It’snotasystematicanalysis,althoughitincludesthis.Asaconsensusdocument,wefollowthemostappropriatemethodology,whichisthemodifiedDelphiprocess.WeinitiallysplitthetaskintofourgroupsforeachofthecomponentsofCEAPclassification:clinical,etiology,anatomy,andpathology.Therewereseveralroundsofdiscussionforeverysuggestionmade.AbriefsummaryofchangescanbeseeninFigure1. Figure1.Abriefsummaryofthe2020revisionsmadetotheCEAPclassification.ModifiedfromLurieF,DeMaeseneerMGR.The2020updateoftheCEAPclassification:whatisnew?EurJVascEndovascSurg.2020;59:859-860.doi:10.1016/j.ejvs.2020.04.020 Dr.Carman:Canyouexplainanddiscussthedifferencesbetweendiscriminativeinstrumentsandevaluativeinstruments?HowdoesadiscriminativeinstrumentlikeCEAPimproveourclinicalpractice? Dr.Lurie:Discriminativeinstrumentsaredesignedtodescribeacondition,patient,ordiseasethatisdifferentfromothers.Usingthisinstrument,youcanplaceapatientintoacertaincategory,whichisdifferentfromanotherpatient.Thecategorythatisassignedtoapatientcananddoeschangeovertime.Ateachpoint,adiscriminativeinstrumenthelpstodetermineifthispatient’sconditionisdifferentorthesame.Theseinstrumentscannotbeusedtogaugethemagnitudeofadifference,toassesstheseverityofthecondition,ortomeasureoutcomes.Theysimplyshowiftheconditionisthesameorifitisdifferent.Evaluativeinstrumentsmeasuretheseverityofacondition,anditschangeovertimeorasaresultofatreatment.Theyincludequality-of-lifequestionnairesandseverityscores,suchastheVenousClinicalSeverityScore. CEAPclassificationisadiscriminativeinstrument.Examinationofapatientwithchronicvenousdiseasehastoincludeadetaileddescriptionforeachofthelowerextremities.TheCEAPclassificationprovidesastructure,helpingtoaddressallimportantaspectsofthemanifestationsofchronicvenousdisease.Thesignsandthesymptomaticstatusarecomponentsoftheclinicalclass,or“C.”Acompletedescriptionofalimbaffectedbychronicvenousdiseaseshouldalwaysincludetheetiology,aswellastheanatomicdistributionofthechanges,andwhetherit’srefluxobstructionoracombinationofthose.Thisisdoneroutinelyineachpractice,butwhenyoudoitsystematically,applyingaCEAPclassification,itwillgiveyouastructureandasimplewaytocommunicatetheresults. Dr.Carman:PossiblythemostoftenusedcomponentofCEAPistheCortheclinicalcomponent.However,inthelasttworevisions,theetiology,anatomy,andphysiologycomponentsaretheonesthathavereallybeenexpandedthemostandhavebecomemoreinclusiveanddescriptiveinnature.Fromyourperspective,doyoufindthismorehelpfulclinicallyorfromareportingpurpose?Whenwereportexpandedportions,particularlytheanatomicandphysiologicportions,wedon’treallyreportthoseinaresearchfashion.Whatisthepracticalityoftheseongoingextensions? Dr.Lurie:ThathasbeenacontentiousissuethroughthehistoryoftheCEAPclassification.Letmeaddressthisfromtwoperspectives—theresearchperspectiveandthentheclinicalperspective.Asaclinicalresearcher,Iincurthesameissuerepeatedly:Wehaveagoodquestionandweknowwehaveenoughexperiencewithpatientstoaddressthequestion,butwhenwelookatthemedicalrecords,wefindgapseverytime;wearenotperfect.Whenwewritetheclinicnote,wefrequentlymisssomethingthatbecomesveryimportantinthefuture.Thisisthemostseriouslimitationofallretrospectivestudies;wedonotsystematicallycollectinformation. Now,letmeaddressthisfromtheclinicalperspective.Forexample,whenweexamineapatientwithchronicvenousdiseasewithlipodermatosclerosis,westartlookingatpossiblecauses.Wewanttoknowwhetheritisaprimarydiseaselimitedtosuperficialreflux,anobstructivediseaseinthefemoropoplitealsegment,oranobstructionintheiliacvein,becausethetreatmentwillbedifferentforeachsetting.Identificationanddocumentationofthisinformationarecomponentsofappropriateclinicalcare.ThosearetheE,A,andPcomponentsofCEAPclassification.Insteadofwritinganentiredescriptionofthepatientanddescribingtheultrasoundorotherimagingfindingseverytime,wesimplycanwriteaCEAPformulathathasallthisinformationincluded.Inpractice,itcreatesaneasystructuretoaddressthemostimportantpartofthedisease. Dr.Carman:Whatdoyouthinkarethetopthreestrengthsofthe2020CEAPclassificationupdate? Dr.Lurie:First,Ithinkthemostimportantupdatewasdoneforetiology:aseparatedistinctionforextravenousandintravenouscausesofsecondarydisease.Theseconditionsmaylooksimilar,withpatientshavingthesamesignsandsymptoms,buttheyrequireverydifferenttreatments.Sometimesclinicalreportsinthejournalsdonotmakesensebecausewedonotknowhowmanyoftheenrolledpatientsinastudyhaveadiseasecausedbyobesityorexternalcompressionversushowmanywerecausedbyasasequelaofdeepveinthrombosis.Ibelieveincludingthetwosubcategoriesofsecondarychronicvenousdiseaseisoneofthebigstrengthsoftherevisedclassification. Secondisthedecisiontoreplacethenumbersintheanatomicdescriptionwithcommonlyusedabbreviations,whichmakesitamorenaturallanguageforthecliniciansandmakesCEAPeasiertouse.IdonotbelievethatmanypractitionersrememberthatA4inCEAPstandsforthesmallsaphenousvein.Replacingthenumberfourwiththeabbreviation“SSV”canbereallyhelpful,especiallyincombinationwiththe“P”ofCEAP.Whenitiswrittenas“As,PrSSV”itclearlydescribesthatonlysuperficialveinsareaffected,andspecificallythatthereisrefluxinthesmallsaphenousvein. Third,themodifierRforrecurrentvaricoseveinsandrecurrentulcersisanexcellentrevision.Recurrentulcersandrecurrentvaricoseveinshavedifferentnaturalhistoryandrequiredifferentmanagementcomparedwiththefirstepisodeofulcerationoruntreatedvaricoseveins. Dr.Carman:Fromyourperspective,youknowulcersdonotalwaysrecurinthesamelocation.Wedoseepatientswhohavehadmultipleepisodesbutnotnecessarilyinthesamelocation.Wasthereanyconsiderationastolocationofrecurrence? Dr.Lurie:Excellentquestion,andyesthatwasdiscussedseveraltimes.Myexperienceisthatarecurrentulcerinthesamelocationmaybemoreofachronicskinconditionandnotalwaysassociatedwithcorrectablevenousabnormalities.Onthecontrary,arecurrenceatadifferentlocationmostoftenindicatesongoingproblemswithvenoushemodynamics,oftencorrectablebyintervention.IncludingalocationoftheulcerintoCEAPmaybeasolution,butitwilladdtothecomplexityandmakeCEAPlessusable.You’reabsolutelyright,chronicvenousdiseaseisnotasimpledisease,andsometimesthecomplexityshouldbesacrificedforpracticalreasons. Dr.Carman:Whatdoyouseeasthebiggestlimitationofthe2020CEAPupdate? Dr.Lurie:Thereareacouplesignificantlimitations.Thefirstispracticality—thereisalwaysacompromise.Ifyoumakeitverypractical,yousacrificeinformation,butifyouareusingtoomuchinformation,itbecomesimpractical.Thatbalancemovesbackandforthallthetime.Itisalwaysgoingtobealimitationofanyclassification,includingCEAP. AnotherlimitationisthatCEAPisfocusedonlyonchronicvenousdisorders.Weknowthatchronicconditionsaresometimestheresultofacuteevents,andacuteconditionscancomplicatechronicdisorders.Forexample,phlebitiscanbeacomplicationofvaricoseveins.ItmaybereasonabletoincludesomeofthecomplicationsinfuturerevisionsofCEAP.Inordertodoso,weneedmoreinformationontheincidenceoftheseconditionsinpatientswithdifferenceclinicalclassesandhowthesecomplicationsaffectthediseasenaturalhistory.ThelimitationsofCEAPshouldbeseenasanopportunitytoexplorerelevantissuesandimprovetheclassificationsinthefuture. Dr.Carman:Forthefirstconsensuspublicationin1996,theAVFsoughtendorsementfromthejointcounciloftheSocietyforVascularSurgery(SVS)andtheNorthAmericanchapteroftheInternationalSocietyforCardiovascularSurgery.YoupreviouslyreferredtotheCEAPclassificationasaconsensusdocuments,butgiventheexpandingvarietyofcliniciansinvolvedinvenousdiseasepractice,whywasthisdocumentlimitedtoAVFsocietymemberswithoutinclusionofothersocietiesmembershipsinthepanelsorendorsementsfromothersocieties? Dr.Lurie:First,IhavetodisclosethatIamnottalkingonbehalfoftheAVFrightnow.You’reexactlycorrect.ThehistoryofCEAPclassificationisthatitwasinitiallydevelopedatthePacificVascularSymposium.ThiswenttothecommissionoftheAVF,anditwasfinalizedthereasaconsensusthatdidrequirethetime,participation,andendorsementofallsocietiestomakethattotallynewclassificationaccessibleandusable. Thatwasaverysuccessfuleffort.Overtime,however,theCEAPclassificationitselfisnolongeraconsensusdocument;it’saclassificationsystemthathasbeenusedformorethan20years.It’saninstrumentthatwasverywellestablishedandpracticallyused,andtheAVFownsthatinstrument.Whenitcametorevisionofthisclassification,therewasnodesiretohaveitbeacomplicatedpoliticalprocessthatmightlastaverylongtimewithoutimprovingtheclassification. TheAVFhasputtogetheraverydiversetaskforceforrevision.AlthoughthemembersofthetaskforcearemembersoftheAVF,theyarealsoprominentmembersofothersocietiesinternationallyandnationally.Thetaskforceisalsosubstantialinsize.Havingsaidthat,publicationofthisclassificationisaninvitationforothersocietiesandotherpractitionerstoexpresstheiropinionsandsuggestions.Moreimportantly,itisaninvitationtoactivelyparticipatewiththeAVF,investigate,andpublishnewevidencethatsupportssuggestedrevisions. Dr.Carman:ArethereanyplansfortheAVFtoworkwithlargerelectronicmedicalrecordscompaniestoincludetheCEAPreportingstandardandclassificationsystemasamoduletofacilitatereporting?Theclinicalresearchershaveawaytouseprospectivelycollecteddata,evenifitisinaretrospectivemannerandhavetheconsistencythatyouarelookingfororincludeitintheSVSdatabase.Doyouthinkthatwouldhelp,orwouldthathaveadetrimentaleffectonadvancingvenousdisease? Dr.Lurie:It’sdefinitelygoingtobeveryhelpful.WeactuallystartedworkingwiththeSVSVascularQualityInitiative(VQI)tointegratetheCEAP2020inusingthevenousmodulesoftheVQI.AsofJune2020,IlearnedthattherevisedCEAPclassificationwasusedastheweb-basedcalculatorthatisveryeasytouseinSpanish,Italian,Portuguese,andRussian;however,itisnotyetavailableinEnglish. Ifyouusethatcalculatoronyourphone,itwillbereallypractical.IlookatacoupleofthosethatIcanunderstand(eg,https://ceap.phlebology-sro.ru/),andit’sreallyaneasytooltouseinaclinicalpractice.IttakessecondstogenerateacompleteCEAPanditwillbeveryusefulifit’sincorporatedintheelectronicmedicalrecords. Advertisement Advertisement AnticoagulationintheCOVID-19Era:WhatWeKnowSoFar WithRaghuKolluri,MS,MD,RVT,FSVM;andGeoffreyD.Barnes,MD,MSc,FACC,FAHA,FSVM,RPVI left-arrow CreatedwithSketch. PreviousArticle DeterminingandApplying“AppropriateUse”ofVenousCare WithKathleenOzsvath,MD,andElnaMasuda,MD NextArticle right-arrow CreatedwithSketch. 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