DNA ligase

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DNA Ligase Selection Chart | NEBDNA Ligase Selection Chart. While more than one ligase may work for your application, the following selection chart presents our recommendations for optimal ...DNA Ligases: Progress and Prospects - NCBI2009年3月27日 · Crystal structures of DNA ligases bound to nucleotide and nucleic acid substrates have illuminated how ligase reaction chemistry is catalyzed, ...T4 DNA ligase structure reveals a prototypical ATP-dependent ...2018年8月29日 · DNA ligases play essential roles in DNA replication and repair. Bacteriophage T4 DNA ligase is the first ATP-dependent ligase enzyme to be ...Engineered DNA ligases with improved activities in vitroThe DNA ligase from bacteriophage T4 is one of the most widely used enzymes in ... ligase-FL-cTF and ligase-HL-cTF are described in the Supplementary data.Differential recruitment of DNA Ligase I and III to DNA repair sitesAbstract. DNA ligation is an essential step in DNA replication, repair and recombination. Mammalian cells contain three DNA Ligases that are not ...The Inhibitory Effect of Non-Substrate and Substrate DNA on ... - PLOS2016年3月8日 · DNA ligases are essential both to in vivo replication, repair and recombination processes, and in vitro molecular biology protocols.Two-tiered enforcement of high-fidelity DNA ligation - Nature2019年11月28日 · DNA ligases catalyze the joining of DNA strands to complete DNA replication, recombination and repair transactions. To protect the integrity ...Full article: DNA ligase III - Taylor & Francis OnlineDNA ligases are crucial for most DNA transactions, including DNA replication, repair, and recombination. Recently, DNA ligase III (Lig3) has been ...Elevated Expression of DNA Ligase I in Human CancersIn DNA ligation reactions mediated by mammalian DNA ligases, ATP is used as a cofactor to form a covalent enzyme-adenylate complex, and in subsequent steps, the ...T4 DNA Ligase - Sigma-AldrichT4 DNA Ligase catalyzes the formation of a phosphodiester bond between the terminal 5′ phosphate and a 3′ hydroxyl groups of duplex DNA or RNA.


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