DNA ligase function
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Structure and function of the DNA ligases encoded by the ... - NCBI2013年9月5日 · Unlike its other nuclear functions, the role of DNA ligase IIIα in alternative NHEJ is independent of its nuclear partner protein, ... tw | twEukaryotic DNA Ligases: Structural and Functional Insights - NCBIThese interactions determine the specific cellular functions of the DNA ligase isozymes. In mammals, defects in DNA ligation have been linked with an ... tw | twDifferential recruitment of DNA Ligase I and III to DNA repair sitesAlthough all three DNA Ligases use the same basic reaction mechanism, they have distinct functions and are not interchangeable ( 3 , 4 ). DNA Ligase I is ...DNA Ligation | NEBIn living organisms, DNA ligases are essential enzymes with critical roles in DNA replication and repair. In the lab, DNA ligation is performed for both cloning ... twStructures of ATP-bound DNA ligase D in a closed domain ...DNA ligases are the sine qua non of genome integrity and essential for DNA replication and repair in all organisms. DNA ligases join 3′-OH and 5′-PO4 ends ...DNA Ligases: Progress and Prospects - Journal of Biological ...DNA ligases are essential guardians of genomic integrity, and ligase ... that most organisms have multiple ligases that either function in DNA replication ...The Inhibitory Effect of Non-Substrate and Substrate DNA on ... - PLOS2016年3月8日 · A >15-fold reduction in T4 DNA ligase self-adenylylation rate when in ... [4] In order to perform their nick-sealing function, DNA ligases ...Full article: DNA ligase III - Taylor & Francis OnlineAbstract · Introduction · Lig3 is Essential for Cellular Viability due to its Role in Mitochondria · Heterologous DNA Ligases can Substitute for Lig3 in ...miR-22 suppresses DNA ligase III addiction in multiple myeloma2018年8月17日 · In this study, we aimed to identify the potential role of DNA ligases as promoters of genomic instability and survival in MM, ...Elevated Expression of DNA Ligase I in Human CancersPurpose: Human DNA ligase I plays an essential role in DNA replication, recombination, and repair by catalyzing the formation of phosphodiester bonds ...
延伸文章資訊
- 1DNA连接反应
Overview. 分子生物学中,连接是指通过形成磷酸二酯键将两个DNA片段连起来。连接反应是由一种叫连接酶的酶催化进行的。在细胞内,连接酶用于修复在DNA复制过程中的单链 ...
- 2DNA连接酶_百度百科
DNA连接酶(DNA Ligase)也称DNA黏合酶,在分子生物学中扮演一个既特殊又关键的角色,那就是连接DNA链一个碱基3'-OH末端和它相邻碱基的5'-P末端,使二者生成磷酸二酯键, ...
- 3ligase - 接合酶 - 國家教育研究院雙語詞彙
出處/學術領域, 英文詞彙, 中文詞彙. 學術名詞 食品科技, ligase, 聯結酶,連接酶. 學術名詞 實驗動物及比較醫學名詞, ligase, 結合酶. 學術名詞 動物學名詞
- 4DNA連接酶(DNA ligase) - 小小整理網站Smallcollation
在分子生物學中扮演一個既特殊又關鍵的角色,那就是把兩條DNA片段(DNA fragments)黏合成一條。無論是雙股或是單股DNA的黏合,DNA黏合酶都可以藉由形成磷酸雙脂鍵將DNA ...
- 5DNA連接酶- 翰林雲端學院
高中生物- DNA連接酶. 參與DNA複製的酵素。 作用:黏合DNA 複製過程中,複製出的一系列 ...